Cargando…
Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models
An important line of postgenomic research seeks to understand how genetic factors can influence epigenetic patterning. Here we review epigenetic effects of chromosomal aneuploidies, focusing on findings in Down syndrome (DS, trisomy 21). Recent work in human DS and mouse models has shown that the ex...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Future Medicine Ltd
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549717/ https://www.ncbi.nlm.nih.gov/pubmed/27911079 http://dx.doi.org/10.2217/epi-2016-0138 |