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Atomistic fingerprint of hyaluronan–CD44 binding

Hyaluronan is a polyanionic, megadalton-scale polysaccharide, which initiates cell signaling by interacting with several receptor proteins including CD44 involved in cell-cell interactions and cell adhesion. Previous studies of the CD44 hyaluronan binding domain have identified multiple widespread r...

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Detalles Bibliográficos
Autores principales: Vuorio, Joni, Vattulainen, Ilpo, Martinez-Seara, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549728/
https://www.ncbi.nlm.nih.gov/pubmed/28715483
http://dx.doi.org/10.1371/journal.pcbi.1005663

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