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Atomistic fingerprint of hyaluronan–CD44 binding
Hyaluronan is a polyanionic, megadalton-scale polysaccharide, which initiates cell signaling by interacting with several receptor proteins including CD44 involved in cell-cell interactions and cell adhesion. Previous studies of the CD44 hyaluronan binding domain have identified multiple widespread r...
Autores principales: | Vuorio, Joni, Vattulainen, Ilpo, Martinez-Seara, Hector |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549728/ https://www.ncbi.nlm.nih.gov/pubmed/28715483 http://dx.doi.org/10.1371/journal.pcbi.1005663 |
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