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Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio

BACKGROUND: Osteopontin (OPN) is an immunoregulatory protein which production increases in both rheumatoid arthritis (RA) and osteoarthritis (OA). Phosphorylated osteopontin (Phospho-OPN) is known to increase macrophage and osteoclast activation, this process is controlled by extracellular tartrate-...

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Detalles Bibliográficos
Autores principales: Luukkonen, Jani, Pascual, Laia Mira, Patlaka, Christina, Lång, Pernilla, Turunen, Sanna, Halleen, Jussi, Nousiainen, Tomi, Valkealahti, Maarit, Tuukkanen, Juha, Andersson, Göran, Lehenkari, Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549736/
https://www.ncbi.nlm.nih.gov/pubmed/28792533
http://dx.doi.org/10.1371/journal.pone.0182904

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