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Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio
BACKGROUND: Osteopontin (OPN) is an immunoregulatory protein which production increases in both rheumatoid arthritis (RA) and osteoarthritis (OA). Phosphorylated osteopontin (Phospho-OPN) is known to increase macrophage and osteoclast activation, this process is controlled by extracellular tartrate-...
Autores principales: | Luukkonen, Jani, Pascual, Laia Mira, Patlaka, Christina, Lång, Pernilla, Turunen, Sanna, Halleen, Jussi, Nousiainen, Tomi, Valkealahti, Maarit, Tuukkanen, Juha, Andersson, Göran, Lehenkari, Petri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549736/ https://www.ncbi.nlm.nih.gov/pubmed/28792533 http://dx.doi.org/10.1371/journal.pone.0182904 |
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