Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use

T-cell therapy of chronic hepatitis B is a novel approach to restore antiviral T-cell immunity and cure the infection. We aimed at identifying T-cell receptors (TCR) with high functional avidity that have the potential to be used for adoptive T-cell therapy. To this end, we cloned HLA-A*02-restricte...

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Detalles Bibliográficos
Autores principales: Wisskirchen, Karin, Metzger, Kai, Schreiber, Sophia, Asen, Theresa, Weigand, Luise, Dargel, Christina, Witter, Klaus, Kieback, Elisa, Sprinzl, Martin F., Uckert, Wolfgang, Schiemann, Matthias, Busch, Dirk H., Krackhardt, Angela M., Protzer, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549754/
https://www.ncbi.nlm.nih.gov/pubmed/28792537
http://dx.doi.org/10.1371/journal.pone.0182936

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