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Upregulation of an inward rectifying K(+) channel can rescue slow Ca(2+) oscillations in K(ATP) channel deficient pancreatic islets
Plasma insulin oscillations are known to have physiological importance in the regulation of blood glucose. In insulin-secreting β-cells of pancreatic islets, K(ATP) channels play a key role in regulating glucose-dependent insulin secretion. In addition, they convey oscillations in cellular metabolis...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549769/ https://www.ncbi.nlm.nih.gov/pubmed/28749940 http://dx.doi.org/10.1371/journal.pcbi.1005686 |