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How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

The specific phenotype of mature differentiated beta cells not only depends on the specific presence of genes that allow beta cell function but also on the selective absence of housekeeping genes (“disallowed genes”) that would interfere with this function. Recent studies have shown that both histon...

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Detalles Bibliográficos
Autores principales: Lemaire, Katleen, Granvik, Mikaela, Schraenen, Anica, Goyvaerts, Lotte, Van Lommel, Leentje, Gómez-Ruiz, Ana, in ‘t Veld, Peter, Gilon, Patrick, Schuit, Frans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549890/
https://www.ncbi.nlm.nih.gov/pubmed/28792951
http://dx.doi.org/10.1371/journal.pone.0181651