Cargando…

Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development

OBJECTIVE: The upregulated expression of heparin binding EGF-like growth factor (HB-EGF) in the vessel and circulation is associated with risk of cardiovascular disease. In this study, we tested the effects of HB-EGF targeting using HB-EGF-specific antisense oligonucleotide (ASO) on the development...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Seonwook, Yang, Lihua, Kim, Seongu, Lee, Richard G., Graham, Mark J., Berliner, Judith A., Lusis, Aldons J., Cai, Lei, Temel, Ryan E., Rateri, Debra L., Lee, Sangderk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549937/ https://www.ncbi.nlm.nih.gov/pubmed/28792970 http://dx.doi.org/10.1371/journal.pone.0182566

Ejemplares similares

Identification of the Cancer Cell Proliferation and Survival Functions of proHB-EGF by Using an Anti-HB-EGF Antibody
por: Sato, Shuji, et al.
Publicado: (2013)

APF, HB-EGF, and EGF biomarkers in patients with ulcerative vs. non-ulcerative interstitial cystitis
por: Zhang, Chen-Ou, et al.
Publicado: (2005)

A Potent Anti-HB-EGF Monoclonal Antibody Inhibits Cancer Cell Proliferation and Multiple Angiogenic Activities of HB-EGF
por: Sato, Shuji, et al.
Publicado: (2012)

Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway
por: Gunawardhana, Niluka, et al.
Publicado: (2018)

The Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the Nucleus
por: Korotkevych, Nataliia V., et al.
Publicado: (2015)

HB-EGF Signaling Is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats
por: Maachi, Hasna, et al.
Publicado: (2020)

Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion
por: Shimura, Takaya, et al.
Publicado: (2012)

Correlation of IL-1 and HB-EGF with endometrial receptivity
por: Wang, Hui, et al.
Publicado: (2018)

Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers
por: Iwamoto, Ryo, et al.
Publicado: (2016)

Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA(1)) Activation in Human Breast and Prostate Cancers
por: David, Marion, et al.
Publicado: (2014)

Small GTP‐binding protein Rap1 mediates EGF and HB‐EGF signaling and modulates EGF receptor expression in HTR‐8/SVneo extravillous trophoblast cells
por: Yoshie, Mikihiro, et al.
Publicado: (2023)

An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation
por: Kim, Yeon Sun, et al.
Publicado: (2023)

Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression
por: van Zon, Jeroen Sebastiaan, et al.
Publicado: (2015)

Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus
por: Shim, Joon W., et al.
Publicado: (2016)

HB-EGF Ameliorates Oxidative Stress-Mediated Uterine Decidualization Damage
por: Yu, Hai-Fan, et al.
Publicado: (2019)

NGF and HB-EGF: Potential Biomarkers that Reflect the Effects of Fesoterodine in Patients with Overactive Bladder Syndrome
por: Kim, Soo Rim, et al.
Publicado: (2015)

Cell-Based Sensors for the Detection of EGF and EGF-Stimulated Ca(2+) Signaling
por: Lee, Euiyeon, et al.
Publicado: (2023)

Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
por: Yamazaki, Satoru, et al.
Publicado: (2003)

Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis
por: Wen, Hui-Ju, et al.
Publicado: (2019)

A Mouse Model of Otitis Media Identifies HB-EGF as a Mediator of Inflammation-Induced Mucosal Proliferation
por: Suzukawa, Keigo, et al.
Publicado: (2014)

HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration
por: Li, Yanyu, et al.
Publicado: (2021)

Proteomic snapshot of the EGF-induced ubiquitin network
por: Argenzio, Elisabetta, et al.
Publicado: (2011)

Expression of PRB, FKBP52 and HB-EGF Relating with Ultrasonic Evaluation of Endometrial Receptivity
por: Wang, Ning, et al.
Publicado: (2012)

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
por: Díaz, Begoña, et al.
Publicado: (2013)

Discovery of HB-EGF binding peptides and their functional characterization in ovarian cancer cell lines
por: Shen, Yanting, et al.
Publicado: (2019)

M2 macrophages reduce the radiosensitivity of head and neck cancer by releasing HB-EGF
por: Fu, Enhui, et al.
Publicado: (2020)

Roles for HB‐EGF in Mesenchymal Stromal Cell Proliferation and Differentiation During Skeletal Growth
por: Li, Ping, et al.
Publicado: (2018)

HB-EGF Activates the EGFR/HIF-1α Pathway to Induce Proliferation of Arsenic-Transformed Cells and Tumor Growth
por: Wang, Lin, et al.
Publicado: (2020)

HB-EGF Plays a Pivotal Role in Mucosal Hyperplasia During Otitis Media Induced by a Viral Analog
por: Sakamoto, Takashi, et al.
Publicado: (2022)

EGF is internalized and degraded
por: Leslie, Mitch
Publicado: (2005)

Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study)
por: Pawlak, Agnieszka, et al.
Publicado: (2023)

Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor
por: Liu, Ning Sheng, et al.
Publicado: (2009)

Effect of blockade of the EGF system on wound healing in patients vaccinated with CIMAvax® EGF
por: Fernández Lorente, Aymara, et al.
Publicado: (2013)

Generation and Characterization of Conditional Heparin-Binding EGF-Like Growth Factor Knockout Mice
por: Oyagi, Atsushi, et al.
Publicado: (2009)

Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites
Publicado: (1995)

Local cortisol activation is involved in EGF-induced immunosuppression
por: Matsumura, Sayaka, et al.
Publicado: (2017)

Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane
por: Hieda, Miki, et al.
Publicado: (2008)

Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF
por: Nanba, Daisuke, et al.
Publicado: (2003)

Restraint Stress Inhibits Mouse Implantation: Temporal Window and the Involvement of HB-EGF, Estrogen and Progesterone
por: Zhao, Li-Hua, et al.
Publicado: (2013)

DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ErbB signaling
por: Liao, Wen-Chieh, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8u8c44t49h453349v7cosvn99k