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An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells

During liver development, hepatoblasts and liver non-parenchymal cells (NPCs) such as liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs) constitute the liver bud where they proliferate and differentiate. Accordingly, we reasoned that liver NPCs would support the maturation...

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Detalles Bibliográficos
Autores principales: Koui, Yuta, Kido, Taketomo, Ito, Toshimasa, Oyama, Hiroki, Chen, Shin-Wei, Katou, Yuki, Shirahige, Katsuhiko, Miyajima, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549957/
https://www.ncbi.nlm.nih.gov/pubmed/28757162
http://dx.doi.org/10.1016/j.stemcr.2017.06.010