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Hyperphosphorylation of RPS6KB1, rather than overexpression, predicts worse prognosis in non-small cell lung cancer patients

RPS6KB1 is the kinase of ribosomal protein S6 which is 70 kDa and is required for protein translation. Although the abnormal activation of RPS6KB1 has been found in types of diseases, its role and clinical significance in non-small cell lung cancer (NSCLC) has not been fully investigated. In this st...

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Detalles Bibliográficos
Autores principales: Chen, Bojiang, Yang, Lan, Zhang, Rui, Gan, Yuncui, Zhang, Wen, Liu, Dan, Chen, Hong, Tang, Huairong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549961/
https://www.ncbi.nlm.nih.gov/pubmed/28792981
http://dx.doi.org/10.1371/journal.pone.0182891

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