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Hyperphosphorylation of RPS6KB1, rather than overexpression, predicts worse prognosis in non-small cell lung cancer patients
RPS6KB1 is the kinase of ribosomal protein S6 which is 70 kDa and is required for protein translation. Although the abnormal activation of RPS6KB1 has been found in types of diseases, its role and clinical significance in non-small cell lung cancer (NSCLC) has not been fully investigated. In this st...
Autores principales: | Chen, Bojiang, Yang, Lan, Zhang, Rui, Gan, Yuncui, Zhang, Wen, Liu, Dan, Chen, Hong, Tang, Huairong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549961/ https://www.ncbi.nlm.nih.gov/pubmed/28792981 http://dx.doi.org/10.1371/journal.pone.0182891 |
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