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Enhanced Energetic State and Protection from Oxidative Stress in Human Myoblasts Overexpressing BMI1

The Polycomb group gene BMI1 is essential for efficient muscle regeneration in a mouse model of Duchenne muscular dystrophy, and its enhanced expression in adult skeletal muscle satellite cells ameliorates the muscle strength in this model. Here, we show that the impact of mild BMI1 overexpression o...

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Detalles Bibliográficos
Autores principales: Dibenedetto, Silvia, Niklison-Chirou, Maria, Cabrera, Claudia P., Ellis, Matthew, Robson, Lesley G., Knopp, Paul, Tedesco, Francesco Saverio, Ragazzi, Martina, Di Foggia, Valentina, Barnes, Michael R., Radunovic, Aleksandar, Marino, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549966/
https://www.ncbi.nlm.nih.gov/pubmed/28735850
http://dx.doi.org/10.1016/j.stemcr.2017.06.009