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Anti-tumor activity of nanomicelles encapsulating CXCR4 peptide antagonist E5

Cancer is the leading cause of death worldwide, and metastasis is the main attribute to cancer death. CXCR4 and its natural ligand CXCL12 have been known to play a critical role in tumorigenesis, angiogenesis and metastasis. Therefore, designing a new CXCR4 antagonist to prevent tumor metastasis wil...

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Detalles Bibliográficos
Autores principales: Fang, Xiaocui, Xie, Hanyi, Duan, Hongyang, Li, Ping, Yousaf, Maryam, Xu, Haiyan, Yang, Yanlian, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549986/
https://www.ncbi.nlm.nih.gov/pubmed/28793338
http://dx.doi.org/10.1371/journal.pone.0182697