Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells

Infection with the helminth Schistosoma (S.) mansoni drives the development of interleukin (IL)-10-producing regulatory B (Breg) cells in mice and man, which have the capacity to reduce experimental allergic airway inflammation and are thus of high therapeutic interest. However, both the involved an...

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Detalles Bibliográficos
Autores principales: Haeberlein, Simone, Obieglo, Katja, Ozir-Fazalalikhan, Arifa, Chayé, Mathilde A. M., Veninga, Henrike, van der Vlugt, Luciën E. P. M., Voskamp, Astrid, Boon, Louis, den Haan, Joke M. M., Westerhof, Lotte B., Wilbers, Ruud H. P., Schots, Arjen, Schramm, Gabriele, Hokke, Cornelis H., Smits, Hermelijn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550006/
https://www.ncbi.nlm.nih.gov/pubmed/28753651
http://dx.doi.org/10.1371/journal.ppat.1006539

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