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Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies
The relevance of topographic cues for commitment of induced pluripotent stem cells (iPSCs) is largely unknown. In this study, we demonstrate that groove-ridge structures with a periodicity in the submicrometer range induce elongation of iPSC colonies, guide the orientation of apical actin fibers, an...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550028/ https://www.ncbi.nlm.nih.gov/pubmed/28757164 http://dx.doi.org/10.1016/j.stemcr.2017.06.016 |