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Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies

The relevance of topographic cues for commitment of induced pluripotent stem cells (iPSCs) is largely unknown. In this study, we demonstrate that groove-ridge structures with a periodicity in the submicrometer range induce elongation of iPSC colonies, guide the orientation of apical actin fibers, an...

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Detalles Bibliográficos
Autores principales: Abagnale, Giulio, Sechi, Antonio, Steger, Michael, Zhou, Qihui, Kuo, Chao-Chung, Aydin, Gülcan, Schalla, Carmen, Müller-Newen, Gerhard, Zenke, Martin, Costa, Ivan G., van Rijn, Patrick, Gillner, Arnold, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550028/
https://www.ncbi.nlm.nih.gov/pubmed/28757164
http://dx.doi.org/10.1016/j.stemcr.2017.06.016