Rho-Associated Kinases and Non-muscle Myosin IIs Inhibit the Differentiation of Human iPSCs to Pancreatic Endoderm

There has been increasing success with the generation of pancreatic cells from human induced pluripotent stem cells (hiPSCs); however, the molecular mechanisms of the differentiation remain elusive. The purpose of this study was to reveal novel molecular mechanisms for differentiation to PDX1(+)NKX6...

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Detalles Bibliográficos
Autores principales: Toyoda, Taro, Kimura, Azuma, Tanaka, Hiromi, Ameku, Tomonaga, Mima, Atsushi, Hirose, Yurie, Nakamura, Masahiro, Watanabe, Akira, Osafune, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550204/
https://www.ncbi.nlm.nih.gov/pubmed/28793244
http://dx.doi.org/10.1016/j.stemcr.2017.07.005

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