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Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells

The differentiation of naive CD8 T cells into effector cytotoxic T lymphocytes upon antigen stimulation is necessary for successful antiviral, and antitumor immune responses. Here, using a mouse model, we describe a dual role for the let-7 microRNAs in the regulation of CD8 T cell responses, where m...

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Detalles Bibliográficos
Autores principales:	Wells, Alexandria C, Daniels, Keith A, Angelou, Constance C, Fagerberg, Eric, Burnside, Amy S, Markstein, Michele, Alfandari, Dominique, Welsh, Raymond M, Pobezinskaya, Elena L, Pobezinsky, Leonid A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550279/ https://www.ncbi.nlm.nih.gov/pubmed/28737488 http://dx.doi.org/10.7554/eLife.26398

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