Cargando…

Teriflunomide slows BVL in relapsing MS: A reanalysis of the TEMSO MRI data set using SIENA

OBJECTIVE: To assess, using structural image evaluation using normalization of atrophy (SIENA), the effect of teriflunomide, a once-daily oral immunomodulator, on brain volume loss (BVL) in patients with relapsing forms of MS enrolled in the phase 3 TEMSO study. METHODS: TEMSO MR scans were analyzed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radue, Ernst-Wilhelm, Sprenger, Till, Gaetano, Laura, Mueller-Lenke, Nicole, Cavalier, Steve, Thangavelu, Karthinathan, Panzara, Michael A., Donaldson, Jessica E., Woodward, Fiona M., Wuerfel, Jens, Wolinsky, Jerry S., Kappos, Ludwig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550381/ https://www.ncbi.nlm.nih.gov/pubmed/28828394 http://dx.doi.org/10.1212/NXI.0000000000000390

Ejemplares similares

The efficacy of teriflunomide in patients who received prior disease-modifying treatments: Subgroup analyses of the teriflunomide phase 3 TEMSO and TOWER studies
por: Freedman, Mark S, et al.
Publicado: (2017)

Effects of teriflunomide treatment on cognitive performance and brain volume in patients with relapsing multiple sclerosis: Post hoc analysis of the TEMSO core and extension studies
por: Sprenger, Till, et al.
Publicado: (2022)

Long-term safety and efficacy of teriflunomide: Nine-year follow-up of the randomized TEMSO study
por: O'Connor, Paul, et al.
Publicado: (2016)

Predicting long-term disability outcomes in patients with MS treated with teriflunomide in TEMSO
por: Sormani, Maria Pia, et al.
Publicado: (2017)

Association of brain volume loss and long-term disability outcomes in patients with multiple sclerosis treated with teriflunomide
por: Sprenger, Till, et al.
Publicado: (2019)

Pre-specified subgroup analyses of a placebo-controlled phase III trial (TEMSO) of oral teriflunomide in relapsing multiple sclerosis
por: Miller, Aaron E, et al.
Publicado: (2012)

Clinical efficacy of teriflunomide over a fixed 2-year duration in the TOWER study
por: Freedman, Mark S, et al.
Publicado: (2018)

Slowing of brain atrophy with teriflunomide and delayed conversion to clinically definite MS
por: Zivadinov, Robert, et al.
Publicado: (2020)

Mission to Siena/
por: Chase, James Hadley, 1906-1985
Publicado: (1977)

A randomized trial of teriflunomide added to glatiramer acetate in relapsing multiple sclerosis
por: Freedman, MS, et al.
Publicado: (2015)

Vision di Siena
Publicado: (1959)

White matter lesion location correlates with disability in relapsing multiple sclerosis
por: Gaetano, Laura, et al.
Publicado: (2020)

Teriflunomide reduces relapse-related neurological sequelae, hospitalizations and steroid use
por: O’Connor, Paul W., et al.
Publicado: (2013)

Groups and Geometries : Siena Conference
por: Martino, Lino, et al.
Publicado: (1998)

Teriflunomide reduces relapses with sequelae and relapses leading to hospitalizations: results from the TOWER study
por: Miller, Aaron E., et al.
Publicado: (2014)

Identification and Characterization of the Transcriptional Regulator ChrB in the Chromate Resistance Determinant of Ochrobactrum tritici 5bvl1
por: Branco, Rita, et al.
Publicado: (2013)

Firenze, Pisa, Siena, San Gimignano
Publicado: (1972)

On the Suspected and Poisonous Fungi of the Territory of Siena
Publicado: (1869)

Subcortical brain segmentation of two dimensional T1-weighted data sets with FMRIB's Integrated Registration and Segmentation Tool (FIRST)
por: Amann, Michael, et al.
Publicado: (2014)

Vida de Santa Catalina de Siena
por: Capua, Francisco de
Publicado: (1947)

Analysis of malignant hyperthermia results in Padua and Siena
por: Tegazzin, Vincenzo, et al.
Publicado: (2014)

Combination of teriflunomide and interferon as follow-up therapy after fingolimod-associated PML
por: Fischer-Barnicol, Bettina, et al.
Publicado: (2020)

Conferenza internazionale di Siena sulle particelle elementari
Publicado: (1964)

Conferenza Internazionale di Siena sulle Particelle Elementari
Publicado: (1964)

PROJECT ADMINISTRATION AGREEMENT KE1926/FP-Siena
por: The European Organization for Nuclear Research, CERN, et al.
Publicado: (2011)

Arch replacement with collared elephant trunks: The Siena approach
por: Neri, Eugenio, et al.
Publicado: (2020)

Monitoring the outpatient process: the Teaching Hospital of Siena experience
por: Guarducci, G, et al.
Publicado: (2023)

Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study: A Randomized Clinical Trial
por: Kappos, Ludwig, et al.
Publicado: (2021)

Improving the SIENA performance using BEaST brain extraction
por: Nakamura, Kunio, et al.
Publicado: (2018)

A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression
por: Nakamura, Yuri, et al.
Publicado: (2018)

First Siena International Conference on Animal Models of Chronic Obstructive Pulmonary Disease, Certosa di Pontignano, University of Siena, Italy, September 30-October 2, 2001
por: Hele, David
Publicado: (2002)

Medical Clinique of Siena, under the Direction of Professor Pietro Burresi, on Diabetes
Publicado: (1866)

SIENA: Semi-automatic semantic enhancement of datasets using concept recognition
por: Grigoriu, Andreea, et al.
Publicado: (2021)

Real-World Observational Evaluation of Hair Thinning in Patients with Multiple Sclerosis Receiving Teriflunomide: Is It an Issue in Clinical Practice?
por: Hendin Travis, Lori, et al.
Publicado: (2018)

Pirfenidone in idiopathic pulmonary fibrosis: real-life experience in the referral centre of Siena
por: Vietri, Lucia, et al.
Publicado: (2020)

Tuberculosis in Siena: evolution of the disease and its treatment, from the Unification of Italy to the 1930s
por: ORSINI, D.
Publicado: (2020)

Vitamin D Deficiency and Cardiovascular Mortality: Retrospective Analysis “Siena Osteoporosis” Cohort
por: Pirrotta, Filippo, et al.
Publicado: (2023)

White matter lesion filling improves the accuracy of cortical thickness measurements in multiple sclerosis patients: a longitudinal study
por: Magon, Stefano, et al.
Publicado: (2014)

An update of teriflunomide for treatment of multiple sclerosis
por: Oh, Jiwon, et al.
Publicado: (2013)

Teriflunomide promotes oligodendroglial differentiation and myelination
por: Göttle, Peter, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bjj1efbv6hlf2rsuoen3ej4dpi