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Single-cell profiling of lineage determining transcription factors in antigen-specific CD4(+) T cells reveals unexpected complexity in recall responses during immune reconstitution
Recent studies of protein and gene expression at the single-cell level have revealed that the memory T-cell compartment is more heterogeneous than previously acknowledged. Identifying different T helper subsets involved in memory responses at the single-cell level is thus necessary to understand the...
Autores principales: | Phetsouphanh, Chansavath, Xu, Yin, Munier, Mee Ling, Zaunders, John J, Kelleher, Anthony D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550558/ https://www.ncbi.nlm.nih.gov/pubmed/28485382 http://dx.doi.org/10.1038/icb.2017.28 |
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