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Evaluation of trained immunity by β-1, 3 (d)-glucan on murine monocytes in vitro and duration of response in vivo
The β-1, 3 (d)-glucan (β-glucan) present in the cell wall of Candida albicans induces epigenetic changes in human monocytes resulting in primed macrophages exhibiting increased cytokine responsiveness to reinfection. This phenomenon is referred to as trained immunity or innate immune memory. However...
Autores principales: | Garcia-Valtanen, Pablo, Guzman-Genuino, Ruth Marian, Williams, David L, Hayball, John D, Diener, Kerrilyn R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550561/ https://www.ncbi.nlm.nih.gov/pubmed/28228641 http://dx.doi.org/10.1038/icb.2017.13 |
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