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Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study
Purpose: Exoskeletons have been developed for rehabilitation of patients with walking impairment due to neurological disorders. Recent studies have shown that the voluntary-driven exoskeleton HAL® (hybrid assistive limb) can improve walking functions in spinal cord injury and stroke. The aim of this...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550721/ https://www.ncbi.nlm.nih.gov/pubmed/28848377 http://dx.doi.org/10.3389/fnins.2017.00449 |
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author | Sczesny-Kaiser, Matthias Kowalewski, Rebecca Schildhauer, Thomas A. Aach, Mirko Jansen, Oliver Grasmücke, Dennis Güttsches, Anne-Katrin Vorgerd, Matthias Tegenthoff, Martin |
author_facet | Sczesny-Kaiser, Matthias Kowalewski, Rebecca Schildhauer, Thomas A. Aach, Mirko Jansen, Oliver Grasmücke, Dennis Güttsches, Anne-Katrin Vorgerd, Matthias Tegenthoff, Martin |
author_sort | Sczesny-Kaiser, Matthias |
collection | PubMed |
description | Purpose: Exoskeletons have been developed for rehabilitation of patients with walking impairment due to neurological disorders. Recent studies have shown that the voluntary-driven exoskeleton HAL® (hybrid assistive limb) can improve walking functions in spinal cord injury and stroke. The aim of this study was to assess safety and effects on walking function of HAL® supported treadmill therapy in patients with limb-girdle muscular dystrophy (LGMD). Materials and Methods: Three LGMD patients received 8 weeks of treadmill training with HAL® 3 times a week. Outcome parameters were 10-meter walk test (10 MWT), 6-minute walk test, and timed-up-and-go test (TUG). Parameters were assessed pre and post training and 6 weeks later (follow-up). Results: All patients completed the therapy without adverse reactions and reported about improvement in endurance. Improvements in outcome parameters after 8 weeks could be demonstrated. Persisting effects were observed after 6 weeks for the 10 MWT and TUG test (follow-up). Conclusions: HAL® treadmill training in LGMD patients can be performed safely and enables an intensive highly repetitive locomotor training. All patients benefitted from this innovative method. Upcoming controlled studies with larger cohorts should prove its effects in different types of LGMD and other myopathies. |
format | Online Article Text |
id | pubmed-5550721 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-55507212017-08-28 Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study Sczesny-Kaiser, Matthias Kowalewski, Rebecca Schildhauer, Thomas A. Aach, Mirko Jansen, Oliver Grasmücke, Dennis Güttsches, Anne-Katrin Vorgerd, Matthias Tegenthoff, Martin Front Neurosci Neuroscience Purpose: Exoskeletons have been developed for rehabilitation of patients with walking impairment due to neurological disorders. Recent studies have shown that the voluntary-driven exoskeleton HAL® (hybrid assistive limb) can improve walking functions in spinal cord injury and stroke. The aim of this study was to assess safety and effects on walking function of HAL® supported treadmill therapy in patients with limb-girdle muscular dystrophy (LGMD). Materials and Methods: Three LGMD patients received 8 weeks of treadmill training with HAL® 3 times a week. Outcome parameters were 10-meter walk test (10 MWT), 6-minute walk test, and timed-up-and-go test (TUG). Parameters were assessed pre and post training and 6 weeks later (follow-up). Results: All patients completed the therapy without adverse reactions and reported about improvement in endurance. Improvements in outcome parameters after 8 weeks could be demonstrated. Persisting effects were observed after 6 weeks for the 10 MWT and TUG test (follow-up). Conclusions: HAL® treadmill training in LGMD patients can be performed safely and enables an intensive highly repetitive locomotor training. All patients benefitted from this innovative method. Upcoming controlled studies with larger cohorts should prove its effects in different types of LGMD and other myopathies. Frontiers Media S.A. 2017-08-08 /pmc/articles/PMC5550721/ /pubmed/28848377 http://dx.doi.org/10.3389/fnins.2017.00449 Text en Copyright © 2017 Sczesny-Kaiser, Kowalewski, Schildhauer, Aach, Jansen, Grasmücke, Güttsches, Vorgerd and Tegenthoff. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Sczesny-Kaiser, Matthias Kowalewski, Rebecca Schildhauer, Thomas A. Aach, Mirko Jansen, Oliver Grasmücke, Dennis Güttsches, Anne-Katrin Vorgerd, Matthias Tegenthoff, Martin Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study |
title | Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study |
title_full | Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study |
title_fullStr | Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study |
title_full_unstemmed | Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study |
title_short | Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study |
title_sort | treadmill training with hal exoskeleton—a novel approach for symptomatic therapy in patients with limb-girdle muscular dystrophy—preliminary study |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550721/ https://www.ncbi.nlm.nih.gov/pubmed/28848377 http://dx.doi.org/10.3389/fnins.2017.00449 |
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