KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway

Melanoma is an aggressive cutaneous malignancy, illuminating the exact mechanisms and finding novel therapeutic targets are urgently needed. In this study, we identified KMT2A as a potential target, which promoted the growth of human melanoma cells. KMT2A knockdown significantly inhibited cell viabi...

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Detalles Bibliográficos
Autores principales: Zhang, Changlin, Song, Chen, Liu, Tianze, Tang, Ranran, Chen, Miao, Gao, Fan, Xiao, Binyi, Qin, Ge, Shi, Fen, Li, Wenbin, Li, Yixin, Fu, Xiaoyan, Shi, Dingbo, Xiao, Xiangsheng, Kang, Lan, Huang, Wenlin, Wu, Xiaojun, Tang, Bing, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550845/
https://www.ncbi.nlm.nih.gov/pubmed/28726783
http://dx.doi.org/10.1038/cddis.2017.285

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