Cargando…
miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer
Colorectal cancer (CRC) is the second major cause of tumor-related deaths. MicroRNAs (miRNAs) have pivotal roles in CRC progression. Here, we describe the effect of miR-181d on CRC cell metabolism and underlying molecular mechanism. Our data firmly demonstrated that knockdown of miR-181d suppressed...
Autores principales: | Guo, Xiaofeng, Zhu, Yuekun, Hong, Xinya, Zhang, Mukun, Qiu, Xingfeng, Wang, Zhenfa, Qi, Zhongquan, Hong, Xuehui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550850/ https://www.ncbi.nlm.nih.gov/pubmed/28749470 http://dx.doi.org/10.1038/cddis.2017.300 |
Ejemplares similares
-
MiR-448 promotes glycolytic metabolism of gastric cancer by downregulating KDM2B
por: Hong, Xuehui, et al.
Publicado: (2016) -
Ubiquitylation of unphosphorylated c-myc by novel E3 ligase SCF(Fbxl8)
por: Bajpai, Sagar, et al.
Publicado: (2022) -
Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers
por: Hong, Xuehui, et al.
Publicado: (2018) -
The circadian E3 ligase complex SCF(FBXL3+CRY) targets TLK2
por: Correia, Stephanie Papp, et al.
Publicado: (2019) -
FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c‐Myc expression
por: Feng, Guangdong, et al.
Publicado: (2022)