The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL

Anaemia is a major global health problem arising from diverse causes and for which improved therapeutic strategies are needed. Erythroid cells can undergo apoptotic cell death and loss of pro-survival BCL-XL is known to trigger apoptosis during late-stage erythroid development. However, the mechanis...

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Detalles Bibliográficos
Autores principales: Delbridge, Alex RD, Aubrey, Brandon J, Hyland, Craig, Bernardini, Jonathan P, Di Rago, Ladina, Garnier, Jean-Marc, Lessene, Guillaume, Strasser, Andreas, Alexander, Warren S, Grabow, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550852/
https://www.ncbi.nlm.nih.gov/pubmed/28682312
http://dx.doi.org/10.1038/cddis.2017.304

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