Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity

Cisplatin-induced ototoxicity is one of the major factors limiting cisplatin chemotherapy. Ototoxicity results from damage to outer hair cells (OHCs) and other regions of the cochlea. At the cellular level, cisplatin increases reactive oxygen species (ROS) leading to cochlear inflammation and apopto...

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Detalles Bibliográficos
Autores principales: Borse, Vikrant, Al Aameri, Raheem F H, Sheehan, Kelly, Sheth, Sandeep, Kaur, Tejbeer, Mukherjea, Debashree, Tupal, Srinivasan, Lowy, Michelle, Ghosh, Sumana, Dhukhwa, Asmita, Bhatta, Puspanjali, Rybak, Leonard P, Ramkumar, Vickram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550861/
https://www.ncbi.nlm.nih.gov/pubmed/28703809
http://dx.doi.org/10.1038/cddis.2017.314

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