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Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia

Here we have explored whether inhibition of autophagy can be used as a treatment strategy for acute myeloid leukemia (AML). Steady-state autophagy was measured in leukemic cell lines and primary human CD34(+) AML cells with a large variability in basal autophagy between AMLs observed. The autophagy...

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Detalles Bibliográficos
Autores principales:	Folkerts, Hendrik, Hilgendorf, Susan, Wierenga, Albertus T J, Jaques, Jennifer, Mulder, André B, Coffer, Paul J, Schuringa, Jan Jacob, Vellenga, Edo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550863/ https://www.ncbi.nlm.nih.gov/pubmed/28703806 http://dx.doi.org/10.1038/cddis.2017.317

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