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Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway

Sonic hedgehog (Shh) signaling is essential for proliferation of cerebellar granule cell progenitors (GCPs) and its misregulation is linked to various disorders, including cerebellar cancer medulloblastoma. The effects of Shh pathway are mediated by the Gli family of transcription factors, which con...

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Detalles Bibliográficos
Autores principales: Quaranta, Roberta, Pelullo, Maria, Zema, Sabrina, Nardozza, Francesca, Checquolo, Saula, Lauer, Dieter Matthias, Bufalieri, Francesca, Palermo, Rocco, Felli, Maria Pia, Vacca, Alessandra, Talora, Claudio, Di Marcotullio, Lucia, Screpanti, Isabella, Bellavia, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550871/
https://www.ncbi.nlm.nih.gov/pubmed/28726779
http://dx.doi.org/10.1038/cddis.2017.326

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