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Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells
Epithelial ovarian cancer (EOC) is one of the most malignant gynecological tumors with a high mortality rate owing to tumor relapse after anticancer therapies. It is widely accepted that a rare tumor cell population, known as cancer stem cells (CSC), is responsible for tumor progression and relapse;...
Autores principales: | Pagotto, Anna, Pilotto, Giorgia, Mazzoldi, Elena Laura, Nicoletto, Maria Ornella, Frezzini, Simona, Pastò, Anna, Amadori, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550872/ https://www.ncbi.nlm.nih.gov/pubmed/28726781 http://dx.doi.org/10.1038/cddis.2017.327 |
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