Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss

No therapies exist to prevent neuronal deficits in multiple sclerosis (MS), because the molecular mechanism responsible for the progressive neurodegeneration is unknown. We previously showed that axon injury-induced neuronal endoplasmic reticulum (ER) stress plays an important role in retinal gangli...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Haoliang, Miao, Linqing, Liang, Feisi, Liu, Xiaodong, Xu, Lin, Teng, Xiuyin, Wang, Qizhao, Ridder, William H, Shindler, Kenneth S, Sun, Yang, Hu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550873/
https://www.ncbi.nlm.nih.gov/pubmed/28726788
http://dx.doi.org/10.1038/cddis.2017.329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550873/
https://www.ncbi.nlm.nih.gov/pubmed/28726788
http://dx.doi.org/10.1038/cddis.2017.329

Ejemplares similares