WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response

There are clear gaps in our understanding of genes and pathways through which cancer cells facilitate survival strategies as they become chemoresistant. Paclitaxel is used in the treatment of many cancers, but development of drug resistance is common. Along with being an antimitotic agent paclitaxel...

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Detalles Bibliográficos
Autores principales: Janczar, Szymon, Nautiyal, Jaya, Xiao, Yi, Curry, Edward, Sun, Mingjun, Zanini, Elisa, Paige, Adam JW, Gabra, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550887/
https://www.ncbi.nlm.nih.gov/pubmed/28749468
http://dx.doi.org/10.1038/cddis.2017.346

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