Physical shearing imparts biological activity to DNA and ability to transmit itself horizontally across species and kingdom boundaries

BACKGROUND: We have recently reported that cell-free DNA (cfDNA) fragments derived from dying cells that circulate in blood are biologically active molecules and can readily enter into healthy cells to activate DNA damage and apoptotic responses in the recipients. However, DNA is not conventionally...

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Detalles Bibliográficos
Autores principales: Raghuram, Gorantla Venkata, Gupta, Deepika, Subramaniam, Siddharth, Gaikwad, Ashwini, Khare, Naveen Kumar, Nobre, Malcolm, Nair, Naveen Kumar, Mittra, Indraneel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550992/
https://www.ncbi.nlm.nih.gov/pubmed/28793862
http://dx.doi.org/10.1186/s12867-017-0098-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550992/
https://www.ncbi.nlm.nih.gov/pubmed/28793862
http://dx.doi.org/10.1186/s12867-017-0098-8

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