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Picropodophyllin (PPP) is a potent rhabdomyosarcoma growth inhibitor both in vitro and in vivo

BACKGROUND: Insulin-like growth factors and insulin are important factors promoting cancer growth and metastasis. The molecules act through IGF1 (IGF1R) and insulin (InsR) receptors. Rhambodmyosarcomas (RMS) overproduce IGF2 – a potent ligand for IGF1R and, at the same time, highly express IGF1 rece...

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Detalles Bibliográficos
Autores principales:	Tarnowski, Maciej, Tkacz, Marta, Zgutka, Katarzyna, Bujak, Joanna, Kopytko, Patrycja, Pawlik, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550998/ https://www.ncbi.nlm.nih.gov/pubmed/28793874 http://dx.doi.org/10.1186/s12885-017-3495-y

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