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Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil

Background: HBV (Hepatitis B Virus) and HCV (Hepatitis C Virus) infections are more prevalent in vulnerable populations than the general population. The objective of this study was to investigate the prevalence of HBV and HCV infection in HIV-positive patients (GI), chronic renal failure (CRF) patie...

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Autores principales: Ribeiro Barbosa, Jakeline, Sousa Bezerra, Cristianne, Carvalho-Costa, Filipe Anibal, Pimentel de Azevedo, Carolina, Lopes Flores, Geane, Baima Colares, Jeová Keny, Malta Lima, Danielle, Lampe, Elisabeth, Melo Villar, Lívia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551231/
https://www.ncbi.nlm.nih.gov/pubmed/28714924
http://dx.doi.org/10.3390/ijerph14070793
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author Ribeiro Barbosa, Jakeline
Sousa Bezerra, Cristianne
Carvalho-Costa, Filipe Anibal
Pimentel de Azevedo, Carolina
Lopes Flores, Geane
Baima Colares, Jeová Keny
Malta Lima, Danielle
Lampe, Elisabeth
Melo Villar, Lívia
author_facet Ribeiro Barbosa, Jakeline
Sousa Bezerra, Cristianne
Carvalho-Costa, Filipe Anibal
Pimentel de Azevedo, Carolina
Lopes Flores, Geane
Baima Colares, Jeová Keny
Malta Lima, Danielle
Lampe, Elisabeth
Melo Villar, Lívia
author_sort Ribeiro Barbosa, Jakeline
collection PubMed
description Background: HBV (Hepatitis B Virus) and HCV (Hepatitis C Virus) infections are more prevalent in vulnerable populations than the general population. The objective of this study was to investigate the prevalence of HBV and HCV infection in HIV-positive patients (GI), chronic renal failure (CRF) patients (GII) and coagulation disorder individuals (GIII). Methods: A cross-sectional study was conducted from June 2014 to March 2015. Serum samples were tested for markers of hepatitis B and C by enzyme-linked immunosorbent assay (ELISA). Sociodemographic, epidemiological, clinical and laboratory data and accompanying statistical analyses were performed using Epi Info™ 7. Results: A total of 348 individuals were recruited, i.e., 154 HIV-positive, 143 CRF and 51 coagulopathy patients. Among them, more than 66% were men, and the predominant age group was 26–35 years in GI and 56–65 years in GIII. Most patients had more than 8 years of education (66.2% in GI, 60.6% in GIII and 46.1% in GII), with a family income between 100–400 dollars in more than 48% of patients. The prevalence of the HBsAg marker was 3.9%, 7% and 3.9%, total anti-HBc was 28.6%, 55.9% and 31.4%, and anti-HCV was 1.3%, 12.6% and 47% for GI, GII and GIII, respectively. However, the prevalence of anti-HBs was greater than 70% in all groups. Conclusions: This study shows a high prevalence of HBV and HCV among specific groups compared to the general population. Factors such as age, income, number of sexual partners, sexually transmitted disease burden, blood transfusion history or blood products and blood transfusions before 1994 were associated with a higher prevalence for these infections.
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spelling pubmed-55512312017-08-11 Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil Ribeiro Barbosa, Jakeline Sousa Bezerra, Cristianne Carvalho-Costa, Filipe Anibal Pimentel de Azevedo, Carolina Lopes Flores, Geane Baima Colares, Jeová Keny Malta Lima, Danielle Lampe, Elisabeth Melo Villar, Lívia Int J Environ Res Public Health Article Background: HBV (Hepatitis B Virus) and HCV (Hepatitis C Virus) infections are more prevalent in vulnerable populations than the general population. The objective of this study was to investigate the prevalence of HBV and HCV infection in HIV-positive patients (GI), chronic renal failure (CRF) patients (GII) and coagulation disorder individuals (GIII). Methods: A cross-sectional study was conducted from June 2014 to March 2015. Serum samples were tested for markers of hepatitis B and C by enzyme-linked immunosorbent assay (ELISA). Sociodemographic, epidemiological, clinical and laboratory data and accompanying statistical analyses were performed using Epi Info™ 7. Results: A total of 348 individuals were recruited, i.e., 154 HIV-positive, 143 CRF and 51 coagulopathy patients. Among them, more than 66% were men, and the predominant age group was 26–35 years in GI and 56–65 years in GIII. Most patients had more than 8 years of education (66.2% in GI, 60.6% in GIII and 46.1% in GII), with a family income between 100–400 dollars in more than 48% of patients. The prevalence of the HBsAg marker was 3.9%, 7% and 3.9%, total anti-HBc was 28.6%, 55.9% and 31.4%, and anti-HCV was 1.3%, 12.6% and 47% for GI, GII and GIII, respectively. However, the prevalence of anti-HBs was greater than 70% in all groups. Conclusions: This study shows a high prevalence of HBV and HCV among specific groups compared to the general population. Factors such as age, income, number of sexual partners, sexually transmitted disease burden, blood transfusion history or blood products and blood transfusions before 1994 were associated with a higher prevalence for these infections. MDPI 2017-07-17 2017-07 /pmc/articles/PMC5551231/ /pubmed/28714924 http://dx.doi.org/10.3390/ijerph14070793 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ribeiro Barbosa, Jakeline
Sousa Bezerra, Cristianne
Carvalho-Costa, Filipe Anibal
Pimentel de Azevedo, Carolina
Lopes Flores, Geane
Baima Colares, Jeová Keny
Malta Lima, Danielle
Lampe, Elisabeth
Melo Villar, Lívia
Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil
title Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil
title_full Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil
title_fullStr Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil
title_full_unstemmed Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil
title_short Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil
title_sort cross-sectional study to determine the prevalence of hepatitis b and c virus infection in high risk groups in the northeast region of brazil
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551231/
https://www.ncbi.nlm.nih.gov/pubmed/28714924
http://dx.doi.org/10.3390/ijerph14070793
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