Cargando…
Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts
BACKGROUND: To limit epidural fibrosis and prevent scar formation/nerve tethering that may contribute to chronic postoperative pain; some surgeons have utilized epidural autologous fat grafts following lumbar microdiscectomy. METHODS: We investigated the correlation between post-microdiscectomy epid...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551283/ https://www.ncbi.nlm.nih.gov/pubmed/28840073 http://dx.doi.org/10.4103/sni.sni_142_17 |
_version_ | 1783256284449996800 |
---|---|
author | Dobran, M. Brancorsini, D. Costanza, M. Della Liverotti, V. Mancini, F. Nasi, D. Iacoangeli, M. Scerrati, M. |
author_facet | Dobran, M. Brancorsini, D. Costanza, M. Della Liverotti, V. Mancini, F. Nasi, D. Iacoangeli, M. Scerrati, M. |
author_sort | Dobran, M. |
collection | PubMed |
description | BACKGROUND: To limit epidural fibrosis and prevent scar formation/nerve tethering that may contribute to chronic postoperative pain; some surgeons have utilized epidural autologous fat grafts following lumbar microdiscectomy. METHODS: We investigated the correlation between post-microdiscectomy epidural scarring [including select magnetic resonance imaging (MRI) studies] and clinical outcomes in 36 patients operated for symptomatic. MRI documented L4-L5 and L5-S1 disk herniations with (18 patients) and without (18 patient) the application of free fat grafts. In addition, histological evaluation of the original fat grafts was performed in 4 patients requiring additional surgery. RESULTS: We found no clear association between the use of autologous graft fats and the clinical outcomes in this study. CONCLUSION: In this preliminary study involving only 36 patients, the prospective randomized use of free autologous fat grafts did not appear to influence outcomes following microdiscectomy. |
format | Online Article Text |
id | pubmed-5551283 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-55512832017-08-24 Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts Dobran, M. Brancorsini, D. Costanza, M. Della Liverotti, V. Mancini, F. Nasi, D. Iacoangeli, M. Scerrati, M. Surg Neurol Int Spine: Original Article BACKGROUND: To limit epidural fibrosis and prevent scar formation/nerve tethering that may contribute to chronic postoperative pain; some surgeons have utilized epidural autologous fat grafts following lumbar microdiscectomy. METHODS: We investigated the correlation between post-microdiscectomy epidural scarring [including select magnetic resonance imaging (MRI) studies] and clinical outcomes in 36 patients operated for symptomatic. MRI documented L4-L5 and L5-S1 disk herniations with (18 patients) and without (18 patient) the application of free fat grafts. In addition, histological evaluation of the original fat grafts was performed in 4 patients requiring additional surgery. RESULTS: We found no clear association between the use of autologous graft fats and the clinical outcomes in this study. CONCLUSION: In this preliminary study involving only 36 patients, the prospective randomized use of free autologous fat grafts did not appear to influence outcomes following microdiscectomy. Medknow Publications & Media Pvt Ltd 2017-08-01 /pmc/articles/PMC5551283/ /pubmed/28840073 http://dx.doi.org/10.4103/sni.sni_142_17 Text en Copyright: © 2017 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Spine: Original Article Dobran, M. Brancorsini, D. Costanza, M. Della Liverotti, V. Mancini, F. Nasi, D. Iacoangeli, M. Scerrati, M. Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts |
title | Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts |
title_full | Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts |
title_fullStr | Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts |
title_full_unstemmed | Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts |
title_short | Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts |
title_sort | epidural scarring after lumbar disc surgery: equivalent scarring with/without free autologous fat grafts |
topic | Spine: Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551283/ https://www.ncbi.nlm.nih.gov/pubmed/28840073 http://dx.doi.org/10.4103/sni.sni_142_17 |
work_keys_str_mv | AT dobranm epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts AT brancorsinid epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts AT costanzamdella epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts AT liverottiv epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts AT mancinif epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts AT nasid epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts AT iacoangelim epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts AT scerratim epiduralscarringafterlumbardiscsurgeryequivalentscarringwithwithoutfreeautologousfatgrafts |