Cargando…
Optical Ring Resonators: A Platform for Biological Sensing Applications
Rapid advances in biochemistry and genetics lead to expansion of the various medical instruments for detection and prevention tasks. On the other hand, food safety is an important concern which relates to the public health. One of the most reliable tools to detect bioparticles (i.e., DNA molecules a...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551303/ https://www.ncbi.nlm.nih.gov/pubmed/28840120 |
_version_ | 1783256289075265536 |
---|---|
author | Sarkaleh, Azadeh Kiani Lahijani, Babak Vosoughi Saberkari, Hamidreza Esmaeeli, Ali |
author_facet | Sarkaleh, Azadeh Kiani Lahijani, Babak Vosoughi Saberkari, Hamidreza Esmaeeli, Ali |
author_sort | Sarkaleh, Azadeh Kiani |
collection | PubMed |
description | Rapid advances in biochemistry and genetics lead to expansion of the various medical instruments for detection and prevention tasks. On the other hand, food safety is an important concern which relates to the public health. One of the most reliable tools to detect bioparticles (i.e., DNA molecules and proteins) and determining the authenticity of food products is the optical ring resonators. By depositing a recipient polymeric layer of target particle on the periphery of an optical ring resonator, it is possible to identify the existence of molecules by calculating the shift in the spectral response of the ring resonators. The main purpose of this paper is to investigate the performance of two structures of optical ring resonators, (i) all-pass and (ii) add-drop resonators for sensing applications. We propose a new configuration for sensing applications by introducing a nanogap in the all-pass ring resonator. The performance of these resonators is studied from sensing point of view. Simulation results, using finite difference time domain paradigm, revealed that the existence of a nanogap in the ring configuration achieves higher amount of sensitivity; thus, this structure is more suitable for biosensing applications. |
format | Online Article Text |
id | pubmed-5551303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-55513032017-08-24 Optical Ring Resonators: A Platform for Biological Sensing Applications Sarkaleh, Azadeh Kiani Lahijani, Babak Vosoughi Saberkari, Hamidreza Esmaeeli, Ali J Med Signals Sens Short Communication Rapid advances in biochemistry and genetics lead to expansion of the various medical instruments for detection and prevention tasks. On the other hand, food safety is an important concern which relates to the public health. One of the most reliable tools to detect bioparticles (i.e., DNA molecules and proteins) and determining the authenticity of food products is the optical ring resonators. By depositing a recipient polymeric layer of target particle on the periphery of an optical ring resonator, it is possible to identify the existence of molecules by calculating the shift in the spectral response of the ring resonators. The main purpose of this paper is to investigate the performance of two structures of optical ring resonators, (i) all-pass and (ii) add-drop resonators for sensing applications. We propose a new configuration for sensing applications by introducing a nanogap in the all-pass ring resonator. The performance of these resonators is studied from sensing point of view. Simulation results, using finite difference time domain paradigm, revealed that the existence of a nanogap in the ring configuration achieves higher amount of sensitivity; thus, this structure is more suitable for biosensing applications. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5551303/ /pubmed/28840120 Text en Copyright: © 2017 Journal of Medical Signals & Sensors http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Short Communication Sarkaleh, Azadeh Kiani Lahijani, Babak Vosoughi Saberkari, Hamidreza Esmaeeli, Ali Optical Ring Resonators: A Platform for Biological Sensing Applications |
title | Optical Ring Resonators: A Platform for Biological Sensing Applications |
title_full | Optical Ring Resonators: A Platform for Biological Sensing Applications |
title_fullStr | Optical Ring Resonators: A Platform for Biological Sensing Applications |
title_full_unstemmed | Optical Ring Resonators: A Platform for Biological Sensing Applications |
title_short | Optical Ring Resonators: A Platform for Biological Sensing Applications |
title_sort | optical ring resonators: a platform for biological sensing applications |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551303/ https://www.ncbi.nlm.nih.gov/pubmed/28840120 |
work_keys_str_mv | AT sarkalehazadehkiani opticalringresonatorsaplatformforbiologicalsensingapplications AT lahijanibabakvosoughi opticalringresonatorsaplatformforbiologicalsensingapplications AT saberkarihamidreza opticalringresonatorsaplatformforbiologicalsensingapplications AT esmaeeliali opticalringresonatorsaplatformforbiologicalsensingapplications |