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Optical Ring Resonators: A Platform for Biological Sensing Applications

Rapid advances in biochemistry and genetics lead to expansion of the various medical instruments for detection and prevention tasks. On the other hand, food safety is an important concern which relates to the public health. One of the most reliable tools to detect bioparticles (i.e., DNA molecules a...

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Autores principales: Sarkaleh, Azadeh Kiani, Lahijani, Babak Vosoughi, Saberkari, Hamidreza, Esmaeeli, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551303/
https://www.ncbi.nlm.nih.gov/pubmed/28840120
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author Sarkaleh, Azadeh Kiani
Lahijani, Babak Vosoughi
Saberkari, Hamidreza
Esmaeeli, Ali
author_facet Sarkaleh, Azadeh Kiani
Lahijani, Babak Vosoughi
Saberkari, Hamidreza
Esmaeeli, Ali
author_sort Sarkaleh, Azadeh Kiani
collection PubMed
description Rapid advances in biochemistry and genetics lead to expansion of the various medical instruments for detection and prevention tasks. On the other hand, food safety is an important concern which relates to the public health. One of the most reliable tools to detect bioparticles (i.e., DNA molecules and proteins) and determining the authenticity of food products is the optical ring resonators. By depositing a recipient polymeric layer of target particle on the periphery of an optical ring resonator, it is possible to identify the existence of molecules by calculating the shift in the spectral response of the ring resonators. The main purpose of this paper is to investigate the performance of two structures of optical ring resonators, (i) all-pass and (ii) add-drop resonators for sensing applications. We propose a new configuration for sensing applications by introducing a nanogap in the all-pass ring resonator. The performance of these resonators is studied from sensing point of view. Simulation results, using finite difference time domain paradigm, revealed that the existence of a nanogap in the ring configuration achieves higher amount of sensitivity; thus, this structure is more suitable for biosensing applications.
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spelling pubmed-55513032017-08-24 Optical Ring Resonators: A Platform for Biological Sensing Applications Sarkaleh, Azadeh Kiani Lahijani, Babak Vosoughi Saberkari, Hamidreza Esmaeeli, Ali J Med Signals Sens Short Communication Rapid advances in biochemistry and genetics lead to expansion of the various medical instruments for detection and prevention tasks. On the other hand, food safety is an important concern which relates to the public health. One of the most reliable tools to detect bioparticles (i.e., DNA molecules and proteins) and determining the authenticity of food products is the optical ring resonators. By depositing a recipient polymeric layer of target particle on the periphery of an optical ring resonator, it is possible to identify the existence of molecules by calculating the shift in the spectral response of the ring resonators. The main purpose of this paper is to investigate the performance of two structures of optical ring resonators, (i) all-pass and (ii) add-drop resonators for sensing applications. We propose a new configuration for sensing applications by introducing a nanogap in the all-pass ring resonator. The performance of these resonators is studied from sensing point of view. Simulation results, using finite difference time domain paradigm, revealed that the existence of a nanogap in the ring configuration achieves higher amount of sensitivity; thus, this structure is more suitable for biosensing applications. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5551303/ /pubmed/28840120 Text en Copyright: © 2017 Journal of Medical Signals & Sensors http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Short Communication
Sarkaleh, Azadeh Kiani
Lahijani, Babak Vosoughi
Saberkari, Hamidreza
Esmaeeli, Ali
Optical Ring Resonators: A Platform for Biological Sensing Applications
title Optical Ring Resonators: A Platform for Biological Sensing Applications
title_full Optical Ring Resonators: A Platform for Biological Sensing Applications
title_fullStr Optical Ring Resonators: A Platform for Biological Sensing Applications
title_full_unstemmed Optical Ring Resonators: A Platform for Biological Sensing Applications
title_short Optical Ring Resonators: A Platform for Biological Sensing Applications
title_sort optical ring resonators: a platform for biological sensing applications
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551303/
https://www.ncbi.nlm.nih.gov/pubmed/28840120
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