Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF

Pituitary tumor-transforming gene 1-binding factor (PTTG1IP; PBF) is a multifunctional glycoprotein, which is overexpressed in a wide range of tumours, and significantly associated with poorer oncological outcomes, such as early tumour recurrence, distant metastasis, extramural vascular invasion and...

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Detalles Bibliográficos
Autores principales: Imruetaicharoenchoke, W, Fletcher, A, Lu, W, Watkins, R J, Modasia, B, Poole, V L, Nieto, H R, Thompson, R J, Boelaert, K, Read, M L, Smith, V E, McCabe, C J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551380/
https://www.ncbi.nlm.nih.gov/pubmed/28676500
http://dx.doi.org/10.1530/ERC-16-0340

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