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Development of Poly Lactic/Glycolic Acid (PLGA) Microspheres for Controlled Release of Rho-Associated Kinase Inhibitor

PURPOSE: The purpose of this study was to investigate the feasibility of poly lactic/glycolic acid (PLGA) as a drug delivery carrier of Rho kinase (ROCK) inhibitor for the treatment of corneal endothelial disease. METHOD: ROCK inhibitor Y-27632 and PLGA were dissolved in water with or without gelati...

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Detalles Bibliográficos
Autores principales: Koda, Sho, Okumura, Naoki, Kitano, Junji, Koizumi, Noriko, Tabata, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551544/
https://www.ncbi.nlm.nih.gov/pubmed/28819566
http://dx.doi.org/10.1155/2017/1598218