Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity

CD8(+) T cells mediate antigen-specific immune responses that can induce rejection of solid tumors. In this process, dendritic cells (DCs) are thought to take up tumor antigens, which are processed into peptides and loaded onto MHC-I molecules, a process called “cross-presentation.” Neither the actu...

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Detalles Bibliográficos
Autores principales: Alloatti, Andrés, Rookhuizen, Derek C., Joannas, Leonel, Carpier, Jean-Marie, Iborra, Salvador, Magalhaes, Joao G., Yatim, Nader, Kozik, Patrycja, Sancho, David, Albert, Matthew L., Amigorena, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551575/
https://www.ncbi.nlm.nih.gov/pubmed/28663435
http://dx.doi.org/10.1084/jem.20170229

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