Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

Adipose triglyceride lipase (ATGL) and its coactivator comparative gene identification-58 (CGI-58) are limiting in cellular triglyceride catabolism. Although ATGL deficiency is compatible with normal skin development, mice globally lacking CGI-58 die postnatally and exhibit a severe epidermal permea...

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Detalles Bibliográficos
Autores principales: Grond, Susanne, Radner, Franz P.W., Eichmann, Thomas O., Kolb, Dagmar, Grabner, Gernot F., Wolinski, Heimo, Gruber, Robert, Hofer, Peter, Heier, Christoph, Schauer, Silvia, Rülicke, Thomas, Hoefler, Gerald, Schmuth, Matthias, Elias, Peter M., Lass, Achim, Zechner, Rudolf, Haemmerle, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551682/
https://www.ncbi.nlm.nih.gov/pubmed/27725204
http://dx.doi.org/10.1016/j.jid.2016.09.025

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