Mutation of the α-tubulin Tuba1a leads to straighter microtubules and perturbs neuronal migration

Brain development involves extensive migration of neurons. Microtubules (MTs) are key cellular effectors of neuronal displacement that are assembled from α/β-tubulin heterodimers. Mutation of the α-tubulin isotype TUBA1A is associated with cortical malformations in humans. In this study, we provide...

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Detalles Bibliográficos
Autores principales: Belvindrah, Richard, Natarajan, Kathiresan, Shabajee, Preety, Bruel-Jungerman, Elodie, Bernard, Jennifer, Goutierre, Marie, Moutkine, Imane, Jaglin, Xavier H., Savariradjane, Mythili, Irinopoulou, Theano, Poncer, Jean-Christophe, Janke, Carsten, Francis, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551700/
https://www.ncbi.nlm.nih.gov/pubmed/28687665
http://dx.doi.org/10.1083/jcb.201607074

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