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Cell cycle–dependent spatial segregation of telomerase from sites of DNA damage

Telomerase can generate a novel telomere at DNA double-strand breaks (DSBs), an event called de novo telomere addition. How this activity is suppressed remains unclear. Combining single-molecule imaging and deep sequencing, we show that the budding yeast telomerase RNA (TLC1 RNA) is spatially segreg...

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Detalles Bibliográficos
Autores principales:	Ouenzar, Faissal, Lalonde, Maxime, Laprade, Hadrien, Morin, Geneviève, Gallardo, Franck, Tremblay-Belzile, Samuel, Chartrand, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551704/ https://www.ncbi.nlm.nih.gov/pubmed/28637749 http://dx.doi.org/10.1083/jcb.201610071

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