Regulation of RhoA by STAT3 coordinates glial scar formation

Understanding how the transcription factor signal transducer and activator of transcription–3 (STAT3) controls glial scar formation may have important clinical implications. We show that astrocytic STAT3 is associated with greater amounts of secreted MMP2, a crucial protease in scar formation. Moreo...

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Detalles Bibliográficos
Autores principales: Renault-Mihara, Francois, Mukaino, Masahiko, Shinozaki, Munehisa, Kumamaru, Hiromi, Kawase, Satoshi, Baudoux, Matthieu, Ishibashi, Toshiki, Kawabata, Soya, Nishiyama, Yuichiro, Sugai, Keiko, Yasutake, Kaori, Okada, Seiji, Nakamura, Masaya, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551705/
https://www.ncbi.nlm.nih.gov/pubmed/28642362
http://dx.doi.org/10.1083/jcb.201610102

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