Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation

Specialized assembly factors facilitate the formation of many macromolecular complexes in vivo. The formation of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requires assembly factors united in protein arginine methyltransferase 5 (PRMT5) and survival...

Descripción completa

Detalles Bibliográficos
Autores principales: Prusty, Archana Bairavasundaram, Meduri, Rajyalakshmi, Prusty, Bhupesh Kumar, Vanselow, Jens, Schlosser, Andreas, Fischer, Utz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551706/
https://www.ncbi.nlm.nih.gov/pubmed/28637748
http://dx.doi.org/10.1083/jcb.201611108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551706/
https://www.ncbi.nlm.nih.gov/pubmed/28637748
http://dx.doi.org/10.1083/jcb.201611108

Ejemplares similares