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Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage

The endoribonuclease Dicer is a key component of the human RNA interference pathway and is known for its role in cytoplasmic microRNA production. Recent findings suggest that noncanonical Dicer generates small noncoding RNA to mediate the DNA damage response (DDR). Here, we show that human Dicer is...

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Detalles Bibliográficos
Autores principales:	Burger, Kaspar, Schlackow, Margarita, Potts, Martin, Hester, Svenja, Mohammed, Shabaz, Gullerova, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551710/ https://www.ncbi.nlm.nih.gov/pubmed/28642363 http://dx.doi.org/10.1083/jcb.201612131

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