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A review of the mechanism of action and clinical applications of sorafenib in advanced osteosarcoma

OBJECTIVE: To summarise the contemporary literature regarding sorafenib and its effectiveness as a novel treatment in advanced osteosarcoma. BACKGROUND: Modern treatment has seen the cure rate of osteosarcoma increase to 65%. However, in patients who do not achieve remission, prognosis is poor, as t...

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Detalles Bibliográficos
Autor principal: Coventon, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552021/
https://www.ncbi.nlm.nih.gov/pubmed/28828294
http://dx.doi.org/10.1016/j.jbo.2017.07.001