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Thermal Stability as a Determinant of AAV Serotype Identity

Currently, there are over 150 ongoing clinical trials utilizing adeno-associated viruses (AAVs) to target various genetic diseases, including hemophilia (AAV2 and AAV8), congenital heart failure (AAV1 and AAV6), cystic fibrosis (AAV2), rheumatoid arthritis (AAV2), and Batten disease (AAVrh.10). Prio...

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Detalles Bibliográficos
Autores principales:	Bennett, Antonette, Patel, Saajan, Mietzsch, Mario, Jose, Ariana, Lins-Austin, Bridget, Yu, Jennifer C., Bothner, Brian, McKenna, Robert, Agbandje-McKenna, Mavis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552060/ https://www.ncbi.nlm.nih.gov/pubmed/28828392 http://dx.doi.org/10.1016/j.omtm.2017.07.003

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