Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro

Pregnancy is associated with increased β-cell proliferation driven by prolactin. Long noncoding RNAs (lncRNA) are the most abundant RNA species in the mammalian genome, yet, their functional importance is mainly elusive. Aims/hypothesis: This study tests the hypothesis that lncRNAs regulate β-cell p...

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Detalles Bibliográficos
Autores principales: Sisino, Giorgia, Zhou, Alex-Xianghua, Dahr, Niklas, Sabirsh, Alan, Soundarapandian, Mangala M., Perera, Ranjan, Larsson-Lekholm, Erik, Magnone, Maria Chiara, Althage, Magnus, Tyrberg, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552087/
https://www.ncbi.nlm.nih.gov/pubmed/28796801
http://dx.doi.org/10.1371/journal.pone.0182371

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