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Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes

The direct reprogramming of cardiac fibroblasts into induced cardiomyocyte (CM)-like cells (iCMs) holds great promise in restoring heart function. We previously found that human fibroblasts could be reprogrammed toward CM-like cells by 7 reprogramming factors; however, iCM reprogramming in human fib...

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Detalles Bibliográficos
Autores principales: Bektik, Emre, Dennis, Adrienne, Prasanna, Prateek, Madabhushi, Anant, Fu, Ji-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552090/
https://www.ncbi.nlm.nih.gov/pubmed/28796841
http://dx.doi.org/10.1371/journal.pone.0183000

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