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Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells

Necrosis, apoptosis and autophagic cell death are the main cell death pathways in multicellular organisms, all with distinct and overlapping cellular and biochemical features. DNA damage may trigger different types of cell death in cancer cells but the molecular events governing the mode of cell dea...

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Detalles Bibliográficos
Autores principales: Kutuk, Ozgur, Aytan, Nurgul, Karakas, Bahriye, Kurt, Asli Giray, Acikbas, Ufuk, Temel, Sehime Gulsun, Basaga, Huveyda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552129/
https://www.ncbi.nlm.nih.gov/pubmed/28796811
http://dx.doi.org/10.1371/journal.pone.0182809