Epigenetic differences between monozygotic twins discordant for amyotrophic lateral sclerosis (ALS) provide clues to disease pathogenesis

Amyotrophic lateral sclerosis (ALS) is a devastating late-onset neurodegenerative disorder in which only a small proportion of patients carry an identifiable causative genetic lesion. Despite high heritability estimates, a genetic etiology for most sporadic ALS remains elusive. Here we report the ep...

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Detalles Bibliográficos
Autores principales: Young, Paul E., Kum Jew, Stephen, Buckland, Michael E., Pamphlett, Roger, Suter, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552194/
https://www.ncbi.nlm.nih.gov/pubmed/28797086
http://dx.doi.org/10.1371/journal.pone.0182638

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