The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is a severe and often fatal systemic malignancy. Malignant cells are capable of escaping host immune surveillance by inactivating cytotoxic lymphoid cells. In this work we discovered a fundamental molecular pathway, which includes ligand-dependent activation of ectopical...

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Detalles Bibliográficos
Autores principales: Gonçalves Silva, Isabel, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Hussain, Rohanah, Siligardi, Giuliano, Ceccone, Giacomo, Berger, Steffen M., Ushkaryov, Yuri A., Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552242/
https://www.ncbi.nlm.nih.gov/pubmed/28750861
http://dx.doi.org/10.1016/j.ebiom.2017.07.018

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