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Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway

Cyclic di-nucleotides (CDN) are potent stimulators of innate and adaptive immune responses. Cyclic di-AMP (CDA) is a promising adjuvant that generates humoral and cellular immunity. The strong STING-dependent stimulation of type I IFN represents a key feature of CDA. However, recent studies suggeste...

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Detalles Bibliográficos
Autores principales:	Lirussi, Darío, Ebensen, Thomas, Schulze, Kai, Trittel, Stephanie, Duran, Veronica, Liebich, Ines, Kalinke, Ulrich, Guzmán, Carlos A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552247/ https://www.ncbi.nlm.nih.gov/pubmed/28754303 http://dx.doi.org/10.1016/j.ebiom.2017.07.016

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